Rheumatoid arthritis-associated gene-gene interaction network for rheumatoid arthritis candidate genes

Rheumatoid arthritis-associated gene-gene interaction network for rheumatoid arthritis candidate genes

Rheumatoid arthritis (RA, MIM 180300) is a chronic and complex autoimmune disease. Using the North American Rheumatoid Arthritis Consortium (NARAC) data set provided in Genetic Analysis Workshop 16 (GAW16), we used the genotype-trait distortion (GTD) scores and proposed analysis procedures to capture the gene-gene interaction effects of multiple susceptibility gene regions on RA. In this paper,...

Evaluating gene × gene and gene × smoking interaction in rheumatoid arthritis using candidate genes in GAW15

We examined the potential gene x gene interactions and gene x smoking interactions in rheumatoid arthritis (RA) using the candidate gene data sets provided by Genetic Analysis Workshop 15 Problem 2. The multifactor dimensionality reduction (MDR) method was used to test gene x gene interactions among candidate genes. The case-only sample was used to test gene x smoking interactions. The best pre...

Gene therapy for rheumatoid arthritis?

Gene therapy for rheumatoid arthritis

Rheumatoid arthritis and osteoporosis

Rheumatoid arthritis and osteoporosis